Xinhe Zhang

Xinhe Zhang

PhD student in Electrical Engineering

Research

You can also find my articles on my Google Scholar profile.

†: First author, ‡: Corresponding author

Publications and Preprints

Stem Cell Engineering

  • Cyborg islets: implanted flexible electronics reveal principles of human islet electrical maturation
    • Science, to appear in 2026.
    • Authors Li, Q.†, Liu, R.†, Lin, Z.†, Zhang, X.†, Wang, W.†, Silva, I.G., Liu, M., Gao, Z., Pollock, S.D., Alvarez-Dominguez, J.R.‡ and Liu, J.‡
  • Flexible Nanoelectronics Reveal Arrhythmogenesis in Transplanted Human Cardiomyocytes
    • Science, 2025.
    • Authors Aoyama, J.†, Liu, R.†, Zhang, X.†, Zhu, A., Luanpaisanon, P., Garbern, J., Cao, F., Barrera, I., Sokol, M., Dasariraju, S., Fandl, H., Gil, E.S., Aleksi, E., Amanuma, T., Velayutham, N., Saucerman, J., Chen, F., Liu, J.‡ and Lee., R.T.‡
  • An AI-Cyborg System for Adaptive Intelligent Modulation of Organoid Maturation
    • bioRxiv, 2024.
    • Authors Liu, R.†, Ren, Z.†, Zhang, X.†, Li, Q., Wang, W., Lin, Z., Lee, R.T., Ding, J., Li, N.‡ and Liu, J.‡

Brain-Machine Interfaces

  • Riemannian Geometry for the Classification of Brain States with Intracortical Brain Recordings
    • Advanced Intelligent Systems, 2025.
    • Authors Marin‐Llobet, A.†, Sánchez‐Manso, S., Manasanch, A., Tresserras, L., Zhang, X., Hua, Y., Zhao, H., Torao‐Angosto, M., Sanchez‐Vives, M.V. and Dalla Porta, L.‡
  • In Vivo Neural Stimulation and Recording using Flexible Bioelectronics
  • Benchmarking spike source localization algorithms in high density probes
    • arXiv, 2025.
    • Authors Zhao, H.†‡, Zhang, X.‡, Marin-Llobet, A., Lin, X. and Liu, J.
  • Plastic-elastomer heterostructure for robust flexible brain-computer interfaces
    • bioRxiv, 2025.
    • Authors Lin, X.†, Zhang, X., Wang, Z., Chen, J., Lee, J., Lee, A.J., Yang, H., Remy, A., Shen, H., He, Y., Zhao, H., Zhang, X., Wang, W., Aljovic, A., Vlassak, J.J., Lu, N., Liu, J.‡
  • Realigning representational drift in mouse visual cortex by flexible brain-computer interfaces
    • bioRxiv, 2024.
    • Authors Zhao, S.†, Shen, H.†, Qin, S., Jiang, S., Tang, X., Lee, M., Zhang, X., Lee, J., Chen, J. and Liu, J.‡

Bio-Inspired and Agentic AI

  • DeviceAgent: An autonomous multimodal AI agent for flexible bioelectronics.
    • bioRxiv, 2025.
    • Authors Lee, J.†, Lin, Z.†, Wang, W.†, Baek, J.†, Lee, A.J., Aljovic, A., Marin-Llobet, A., Zhang, X., Liu, R., Li, N. and Liu, J.‡
  • An AI Agent for cell-type specific brain computer interfaces
    • bioRxiv, 2025.
    • Authors Marin-Llobet, A.†, Lin, Z.†, Baek, J.†, Aljovic, A., Zhang, X., Lee, A.J., Wang, W., Lee, J., Shen, H., He, Y., Li, N., Liu, J.‡
  • An autonomous AI agent for universal behavior analysis
    • bioRxiv, 2025.
    • Authors Aljovic, A.†‡ Lin, Z.†‡, Wang, W., Zhang, X., Marin-Llobet, A., Liang, N., Canales, B., Lee, J., Baek, J., Liu, R., Li, C., Li, N., Liu, J.‡
  • Spatial transcriptomics AI agent charts hPSC-pancreas maturation in vivo
    • bioRxiv, 2025.
    • Authors Lin, Z.†, Wang, W.†, Marin-Llobet, A., Li, Q., Pollock, S.D., Sui, X., Almir Aljovic, Lee, J., Baek, J., Liang, N., Zhang, X., Wang, C.K., Huang, J., Liu, M., Gao, Z., Sheng, H., Du, J., Lee, S.J., Wang, B., He, Y., Ding, J., Wang, X., Alvarez-Dominguez, J.R.‡ and Liu, J.‡
  • Spike sorting AI agent
    • bioRxiv, 2025.
    • Authors Lin, Z.†, Marin-Llobet, A.†, Baek, J., He, Y., Lee, J., Wang, W., Zhang, X., Lee, A.J., Liang, N., Du, J., Ding, J., Li, N. and Liu. J.‡
  • Drift to Remember
    • arXiv, 2024.
    • Authors Du, J.†, Zhang, X., Shen, H., Xian, X., Wang, G., Zhang, J., Yang, Y., Li, N., Liu, J.‡ and Ding, J.‡

Miscellaneous Research

  • Explainable multi-task learning for multi-modality biological data analysis
    • Nature communications, 2023.
    • Authors Tang, X.†, Zhang, J.†, He, Y.†, Zhang, X., Lin, Z., Partarrieu, S., Hanna, E.B., Ren, Z., Shen, H., Yang, Y., Wang, X., Li, N., Ding, J.‡ and Liu, J.‡
  • Carla simulated data for rare road object detection
  • Error-In-Variables Methods for Efficient System Identification with Finite-Sample Guarantees
    • arXiv, 2025.
    • Authors Zhang, Y.†, Zhang, X., Liu, J. and Li, N.‡

Awards and Talks

Awards and Honors

Talks and Presentations

  • 2025 Harvard University Center for Brain Science Retreat (Poster)
  • 2025 Eric and Wendy Schmidt Center Biomedical Science and AI Symposium (Poster)
  • 2025 National Science Foundation Workshop on Reinforcement Learning (Poster)
  • 2024 National Institutes of Health BRAIN NeuroAI Workshop (Poster)
  • 2024 Harvard University BE131 Neuroengineering (Guest lecture)
  • 2024 Harvard University BE129 Introduction to Bioelectronics (Guest lecture)